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Irish Wolfhound - Health Issues
Written by Hugh McManus   

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Friday, 05 September 2008 06:00

Lactated Ringer's Solution is an ionic solution of sodium, potassium, calcium, chloride and lactate that is isotonic (is similar in its ionic strength) with blood.  The solution is administered subcutaneously to irish Wolfhounds, particularly those that are suffering from renal failure.

The British physiologist Sydney Ringer invented the saline solution in the latter half of the nineteenth century while working at University College Hospital, London.  Lactate was added to the solution by Alexis Hartmann as a pH buffer.

One of the indications of rental failure is a buildup of creatinine in the blood.  Creatinine is a metabolite of creatine phosphate in muscle and is constantly produced by the body.  Creatinine is filtered by the kidneys and an increase in concentration is indicative of renal failure.  Byproducts of the metabolism of lactate counteract acidosis due to elevated creatinine levels.  Treatment with the solution can counteract the buildup of creatinine in the blood.

 

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